Sodium Iodide → Cyclohexyloxycarbonyloxymethyl iodide

HRID 892920Notes

Reaction equation

HRID 892920 reaction equation
[C:1](=[O:12])([O:5][CH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)[O:2][CH2:3]Cl.[I-:13].[Na+]>CC(C)=O>[C:1](=[O:12])([O:5][CH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)[O:2][CH2:3][I:13]

Participants

4

Reactant 2

HCID 5238Sodium IodideHCID 13603586Chloromethyl cyclohexyl carbonate

Product 1

HCID 11087296Cyclohexyloxycarbonyloxymethyl iodide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A solution of 0.78 g of chloromethyl cyclohexyl carbonate and 1.0 g of sodium iodide in 15 ml of acetone is stirred at room temperature for 16 hours and then concentrated under reduced pressure. The residue is extracted with ether and the solvent is distilled off under reduced pressure to give the title compound as pale yellow oil.

Workup

  1. concentrationconcentrated under reduced pressure
  2. extractionThe residue is extracted with ether
  3. distillationthe solvent is distilled off under reduced pressure

Sources & evidence

ORD record
ord-f6f0345371204717bf40763b7b156307
Source dataset
uspto-grants-1992_06
Patent number
US05120841

Reaction notes

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