Hydrochloric Acid → HCID 19894619, compound

HRID 893016Notes

Reaction equation

HRID 893016 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([CH2:11][CH2:12][CH2:13][CH2:14][N:15]2[CH2:20][CH2:19][N:18]([C:21]3[C:26]([NH:27][CH2:28][CH3:29])=[CH:25][CH:24]=[CH:23][N:22]=3)[CH2:17][CH2:16]2)[CH:5]=[C:6]([CH3:10])[C:7]=1[O:8][CH3:9].CCOCC.[ClH:35]>CCOCC.CC(C)=O>[ClH:35].[ClH:35].[CH3:1][C:2]1[CH:3]=[C:4]([CH2:11][CH2:12][CH2:13][CH2:14][N:15]2[CH2:20][CH2:19][N:18]([C:21]3[C:26]([NH:27][CH2:28][CH3:29])=[CH:25][CH:24]=[CH:23][N:22]=3)[CH2:17][CH2:16]2)[CH:5]=[C:6]([CH3:10])[C:7]=1[O:8][CH3:9]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 19894524HCID 19894524, compound

Product 1

HCID 19894619HCID 19894619, compound

Reagents, catalysts & solvents 1

HCID 21584533Acetone diethyletherSolvent

Procedure

2-[4-(4-(3,5-Dimethyl-4-methoxyphenyl)butyl)piperazin-1-yl]-N-ethyl-3-pyridineamine (EXAMPLE 43) is dissolved in ether/acetone and treated in excess with ether which was saturated with hydrogen chloride gas. The salt is filtered, dried under reduced pressure to give the title compound.

Workup

  1. filtrationThe salt is filtered
  2. customdried under reduced pressure

Sources & evidence

ORD record
ord-ef99f033f00f46dfba2a50732f4dbb84
Source dataset
uspto-grants-1992_06
Patent number
US05120843

Reaction notes

Loading…