Triethylamine → HCID 19096842, compound

HRID 893223Notes

Reaction equation

HRID 893223 reaction equation
[Br:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[C:4]([CH3:9])[CH:3]=1.Cl[C:11]([C:13]([O:20][CH3:21])([O:18][CH3:19])[C:14]([O:16][CH3:17])=[O:15])=[O:12].C(N(CC)CC)C>>[Br:1][C:2]1[CH:8]=[CH:7][C:5]([NH:6][C:11](=[O:12])[C:13]([O:20][CH3:21])([O:18][CH3:19])[C:14]([O:16][CH3:17])=[O:15])=[C:4]([CH3:9])[CH:3]=1

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 114234-Bromo-2-methylanilineHCID 19096901HCID 19096901, compound

Product 1

HCID 19096842HCID 19096842, compoundYield 50%

Procedure

4-Bromo-2-methylaniline (2.83 grams, 0.01 mole), methyl chlorocarbonyl(dimethoxy)acetate (2.99 grams, 0.01 mole), prepared in Part A, and triethylamine (1.54 grams, 0.015 mole) were reacted in a manner similar to the procedure described in Example I to give 1.73 grams (0.005 mole) of methyl 3-[(4-bromo-2-methylphenyl)amino]-2,2-dimethoxy-3-oxopropanoate having a melting point of 99° C.-103° C.

Workup

  1. customwere reacted in a manner similar to the procedure

Sources & evidence

ORD record
ord-6409dad00f444f61931132a6073ac710
Source dataset
uspto-grants-1992_06
Patent number
US05123951

Reaction notes

Loading…