Triethylamine → HCID 19096815, compound

HRID 893224Notes

Reaction equation

HRID 893224 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([Cl:9])[CH:8]=1)[NH2:5].Cl[C:11]([C:13]([O:20][CH3:21])([O:18][CH3:19])[C:14]([O:16][CH3:17])=[O:15])=[O:12].C(N(CC)CC)C>C(Cl)Cl>[Cl:1][C:2]1[CH:3]=[C:4]([NH:5][C:11](=[O:12])[C:13]([O:20][CH3:21])([O:18][CH3:19])[C:14]([O:16][CH3:17])=[O:15])[CH:6]=[C:7]([Cl:9])[CH:8]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 122813,5-DichloroanilineHCID 19096901HCID 19096901, compound

Product 1

HCID 19096815HCID 19096815, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

In a manner similar to the procedure described in Example I, 3,5-dichloroaniline was reacted with methyl chlorocarbonyl(dimethoxy)acetate, prepared as described in Example LXV Part A, employing triethylamine as the acid acceptor in methylene chloride solution. The methyl 3-[(3,5-dichlorophenyl)amino]-2,2-dimethoxy-3-oxopropanoate product (2.31 grams, 0.007 mole) was obtained as colorless crystals having a melting point of 160° C.-164° C.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-4831ed32bc094050bbcedc31cc5007ff
Source dataset
uspto-grants-1992_06
Patent number
US05123951

Reaction notes

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