Hydrochloric Acid → HCID 21162739, compound

HRID 894186Notes

Reaction equation

HRID 894186 reaction equation
[NH2:1][CH:2]([C:5]1[CH:20]=[CH:19][C:8]2[O:9][CH2:10][C:11]3[CH:18]=[CH:17][CH:16]=[CH:15][C:12]=3[C:13](=[O:14])[C:7]=2[CH:6]=1)[C:3]#[N:4].Cl.[OH-:22].[NH4+]>>[NH2:1][CH:2]([C:5]1[CH:20]=[CH:19][C:8]2[O:9][CH2:10][C:11]3[CH:18]=[CH:17][CH:16]=[CH:15][C:12]=3[C:13](=[O:14])[C:7]=2[CH:6]=1)[C:3]([NH2:4])=[O:22]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 14923Ammonium HydroxideHCID 21162742HCID 21162742, compound

Product 1

HCID 21162739HCID 21162739, compound

Procedure

Stir at room temperature 5.0 gm. of the aminoacetonitrile of Step B in 30 ml. of concentrated hydrochloric acid for 30 minutes. Slowly pour the reaction mixture into cold ammonium hydroxide. Extract the mixture with ether and dry over sodium sulfate. Evaporate the extract to dryness to obtain the title product.

Workup

  1. extractionExtract the mixture with ether
  2. dry with materialdry over sodium sulfate
  3. customEvaporate the
  4. extractionextract to dryness

Sources & evidence

ORD record
ord-ec82070061214922849f32b600f5faf9
Source dataset
uspto-grants-1981_08
Patent number
US04282365

Reaction notes

Loading…