Hydrogen Peroxide → HCID 21162717, compound

HRID 894204Notes

Reaction equation

HRID 894204 reaction equation
[CH3:1][S:2][CH:3]1[C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=2[CH2:7][O:6][C:5]2[CH:14]=[CH:15][C:16]([C:18]([OH:20])=[O:19])=[CH:17][C:4]1=2.[OH:21]O>C(O)(=O)C>[CH3:1][S:2]([CH:3]1[C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=2[CH2:7][O:6][C:5]2[CH:14]=[CH:15][C:16]([C:18]([OH:20])=[O:19])=[CH:17][C:4]1=2)=[O:21]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 12929146HCID 12929146, compound

Product 1

HCID 21162717HCID 21162717, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
40 °C

Procedure

Dissolve with warming 380 mg. of 6,11-dihydro-11-methylthiodibenz[b,e]oxepin-2-carboxylic acid in 38 ml. of glacial acetic acid. Place the reaction mixture in an oil bath at 40° C. and add 1.5 ml. of 30% hydrogen peroxide. Stir the mixture at 40° C. for 3 1/2 hours until the solution clears. Dilute with 300 ml. of water and separate the precipitate by filtration to obtain the title product.

Workup

  1. dissolutionDissolve
  2. temperaturewith warming 380 mg
  3. customat 40° C.
  4. additionadd 1.5 ml
  5. additionDilute with 300 ml
  6. customof water and separate the precipitate
  7. filtrationby filtration

Sources & evidence

ORD record
ord-eaf41d712fc5446ca47607de6907a359
Source dataset
uspto-grants-1981_08
Patent number
US04282365

Reaction notes

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