Potassium Carbonate → HCID 21161169, compound

HRID 894407Notes

Reaction equation

HRID 894407 reaction equation
C[O:2][CH:3](OC)[CH:4]([CH2:13][CH3:14])[CH2:5][CH2:6][CH2:7][O:8][S:9]([CH3:12])(=[O:11])=[O:10].C(=O)([O-])[O-].[K+].[K+]>C(OCC)C.Cl>[CH2:13]([CH:4]([CH2:5][CH2:6][CH2:7][O:8][S:9]([CH3:12])(=[O:10])=[O:11])[CH:3]=[O:2])[CH3:14]

Participants

5

Reactant 2

HCID 11430Potassium CarbonateHCID 21161168HCID 21161168, compound

Product 1

HCID 21161169HCID 21161169, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 3283Diethyl EtherSolvent

Procedure

To a solution of 2.55 g (0.01 mol) of 4-dimethoxymethyl-1-methanesulfonyloxyhexane in 40 ml of diethyl ether, 20 ml of 1.2 N HCl was added and the mixture stirred at reflux for 12 h. Solid potassium carbonate (3 g) was slowly added, the organic layer separated and the aqueous layer extracted with 25 ml of ether. The combined ether solutions were washed with brine, dried over magnesium sulfate, filtered and concentrated to 1.66 g of the aldehyde IXe;

Workup

  1. temperatureat reflux for 12 h
  2. customthe organic layer separated
  3. extractionthe aqueous layer extracted with 25 ml of ether
  4. washThe combined ether solutions were washed with brine
  5. dry with materialdried over magnesium sulfate
  6. filtrationfiltered
  7. concentrationconcentrated to 1.66 g of the aldehyde IXe

Sources & evidence

ORD record
ord-13d782134b4749f98d4d8cd61de3061f
Source dataset
uspto-grants-1981_08
Patent number
US04283536

Reaction notes

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