Water → HCID 12926286, compound

HRID 894512Notes

Reaction equation

HRID 894512 reaction equation
[O:1]([CH:8]([NH:13][C:14](=[O:22])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[OH:21])[C:9]([Cl:12])([Cl:11])[Cl:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:23][N:24]=[C:25]=[O:26].O>CC(C)=O.C(N(CC)CC)C>[O:1]([CH:8]([NH:13][C:14](=[O:22])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[O:21][C:25](=[O:26])[NH:24][CH3:23])[C:9]([Cl:10])([Cl:11])[Cl:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

6

Reactant 3

HCID 962WaterHCID 12228Methyl IsocyanateHCID 12922489HCID 12922489, compound

Product 1

HCID 12926286HCID 12926286, compoundYield 36.3%

Reagents, catalysts & solvents 2

HCID 8471TriethylamineCatalystHCID 180AcetoneSolvent

Procedure

10 g of N-(1'-phenoxy-2',2',2'-trichloroethyl)-2-hydroxybenzamide and 1.8 g of methyl isocyanate were dissolved in 150 mml of acetone. Two or three drops of triethylamine were added to the solution under stirring. After allowing to stand overnight, the reaction mixture was poured into water and the crystals which thus resulted were recrystallized from methanol to obtain 4.2 g of N-(1'-phenoxy-2',2',2'-trichloroethyl)-2-methylcarbamoyloxybenzamide as white crystals. Melting point: 138°-141° C.

Workup

  1. customthe crystals which thus resulted
  2. customwere recrystallized from methanol

Sources & evidence

ORD record
ord-7a1d9cbc0b9b4d8a826c7eea61a89c84
Source dataset
uspto-grants-1981_08
Patent number
US04284628

Reaction notes

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