Hydrochloric Acid → HCID 20512452, compound

HRID 894605Notes

Reaction equation

HRID 894605 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][CH2:9][CH:10]([NH:12][C:13]2[C:18]([CH3:19])=[CH:17][CH:16]=[CH:15][C:14]=2[CH3:20])[CH3:11])=[CH:4][CH:3]=1.ClC(C)[CH2:23][NH:24]C1C=CC(Cl)=CC=1.CC1C=CC=C(C)C=1N.Cl>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:9][CH:10]([CH3:11])[N:12]([C:13]3[C:18]([CH3:19])=[CH:17][CH:16]=[CH:15][C:14]=3[CH3:20])[C:23]2=[NH:24])=[CH:4][CH:3]=1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 68962,6-DimethylanilineHCID 20512446HCID 20512446, compoundHCID 20512458HCID 20512458, compound

Product 1

HCID 20512452HCID 20512452, compoundYield 50.9%

Procedure

1-(4'-Chlorophenyl-amino)-2-(2',6'-dimethylphenylamino)-propane, applied as starting substance, is obtained with a yield of 50.9% by reacting N-(β-chloropropyl)-4-chloro-aniline, a compound prepared as described in Example 27, point (b), with 2,6-dimethylaniline according to the method given in Example 25, point (a). The hydrochloride of the product melts at 170°-178° C.

Workup

  1. customis obtained with a yield of 50.9%
  2. customa compound prepared

Sources & evidence

ORD record
ord-1eb21e8289b747389416286cf9c13e47
Source dataset
uspto-grants-1981_08
Patent number
US04284642

Reaction notes

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