反应详情

The sodium salt is formed from 2.4 g. (0.1 moles) of sodium hydride and 19.73 g. (0.1 moles) of cyclododecanone oxime in a toluenic medium, then it is reacted with 18.0 g. (0.11 moles) of 1-chloro-3-morpholinopropane. Thereafter one proceeds as in Example 1. Yield: 22.22 g. (68.5%). Hydrogen fumarate, m.p.: 118°-120° C.