Ethyl Acetate → 5-Aminoacenaphthene

HRID 898410Notes

Reaction equation

HRID 898410 reaction equation
[N+:1]([C:4]1C=C[C:12]2[C:15]3[C:5]=1[CH2:6][CH2:7][C:8]=3[CH:9]=[CH:10][CH:11]=2)([O-])=O.C(O[CH2:20][CH3:21])(=O)C>[Pd]>[CH2:15]1[C:12]2=[C:20]3[C:21](=[CH:9][CH:10]=[CH:11]2)[C:4]([NH2:1])=[CH:5][CH:6]=[C:7]3[CH2:8]1

Participants

4

Reactant 2

HCID 8857Ethyl AcetateHCID 97618Acenaphthene, 3-nitro-

Product 1

HCID 625475-Aminoacenaphthene

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

A mixture of 5 and 3-nitroacenaphthene was reduced with Pd/C in ethyl acetate under hydrogen at 40 psi pressure and the resulting amines were separated by recrystallization from cyclohexane/ethyl acetate.

Workup

  1. customthe resulting amines were separated by recrystallization from cyclohexane/ethyl acetate

Sources & evidence

ORD record
ord-740902d564ae4dc9875a50fb861a96b0
Source dataset
uspto-grants-2008_04
Patent number
US07351743B1

Reaction notes

Loading…