反应详情

A suspension of 0.700 g (2.884 mmol) (2-chloro-4-nitro-benzyl)-diethyl-amine (Z35a) and 0.400 g Raney nickel in 20 mL THF was hydrogenated for 7.5 h at RT and 25 psi. The catalyst was filtered off and the filtrate was evaporated down i. vac. The crude product was purified by column chromatography (Alox, neutral, act. II-III, petroleum ether/EtOAc 4:1).

1. filtrationThe catalyst was filtered off
2. customthe filtrate was evaporated down i
3. customThe crude product was purified by column chromatography (Alox, neutral, act. II-III, petroleum ether/EtOAc 4:1)