Potassium Carbonate → HCID 21919275, compound

HRID 898695Notes

Reaction equation

HRID 898695 reaction equation
[Cl:1][C:2]1[N:7]=[N:6][C:5]([CH3:8])=[C:4]([CH2:9][CH2:10][CH3:11])[CH:3]=1.C1C=C(Cl)C=C(C(OO)=[O:20])C=1.C([O-])([O-])=O.[K+].[K+]>C(Cl)Cl>[Cl:1][C:2]1[N:7]=[N+:6]([O-:20])[C:5]([CH3:8])=[C:4]([CH2:9][CH2:10][CH3:11])[CH:3]=1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 70297m-Chloroperbenzoic acidHCID 219192706-Chloro-3-methyl-4-propylpyridazine

Product 1

HCID 21919275HCID 21919275, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 6-chloro-3-methyl-4-propyl-pyridazine (8.03 g, 47.06 mmol) in CH2Cl2 (200 ml) is added mCPBA (11.6 g, 77%, 51.77 mmol). The mixture is stirred at room temperature overnight. Saturated K2CO3 aqueous solution (50 ml) is added and the layers are separated. The organic layer is then washed with brine (100 ml) and dried (Na2SO4) and evaporated, which provides the title product as a light yellow oil.

Workup

  1. customthe layers are separated
  2. washThe organic layer is then washed with brine (100 ml)
  3. dry with materialdried (Na2SO4)
  4. customevaporated

Sources & evidence

ORD record
ord-4acc1cb3f1b943b7a127da1e5910de37
Source dataset
uspto-grants-2008_04
Patent number
US07351826B2

Reaction notes

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