Acetic Acid → 6-Chloro-9a-(2-fluoroethyl)-7-methoxy-9,9a-dihydro-1H-fluoren-3(2H)-one

HRID 89893Notes

Reaction equation

HRID 89893 reaction equation
[CH2:26]1[CH2:27][NH:28][CH2:29][CH2:30]1.[CH3:22][C:23](=[O:24])[OH:25].[CH3:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[CH3:38][CH2:39][O:40][C:41]([CH3:42])=[O:43].[Cl:1][c:2]1[c:3]([O:20][CH3:21])[cH:4][c:5]2[c:9]([cH:10]1)[C:8](=[O:11])[C:7]([CH2:12][CH2:13][C:14]([CH3:15])=[O:16])([CH2:17][CH2:18][F:19])[CH2:6]2>>[Cl:1][c:2]1[c:3]([O:20][CH3:21])[cH:4][c:5]2[c:9]([cH:10]1)[C:8]1=[CH:15][C:14](=[O:16])[CH2:13][CH2:12][C:7]1([CH2:17][CH2:18][F:19])[CH2:6]2

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 1140TolueneHCID 8857Ethyl AcetateHCID 31268PyrrolidineHCID 57603342HCID 57603342, compound

Product 1

HCID 534381796-Chloro-9a-(2-fluoroethyl)-7-methoxy-9,9a-dihydro-1H-fluoren-3(2H)-one

Sources & evidence

ORD record
ord-236cdfb9a1d540bc86001b902419ff89
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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