Hydrochloric Acid → 7-Chloro-4-oxo-3-(phenoxycarbonylamino-methyl)-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester

HRID 89989Notes

Reaction equation

HRID 89989 reaction equation
[CH3:2][O:3][C:4](=[O:5])[c:6]1[n:7](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[c:8]2[cH:9][c:10]([Cl:19])[cH:11][cH:12][c:13]2[c:14](=[O:18])[c:15]1[CH2:16][NH2:17].[CH:36]([N:37]([CH2:38][CH3:39])[CH:40]([CH3:41])[CH3:42])([CH3:43])[CH3:44].[Cl:26][C:27](=[O:28])[O:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1.[Cl:45][CH2:46][Cl:47].[ClH:1]>>[CH3:2][O:3][C:4](=[O:5])[c:6]1[n:7](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[c:8]2[cH:9][c:10]([Cl:19])[cH:11][cH:12][c:13]2[c:14](=[O:18])[c:15]1[CH2:16][NH:17][C:27](=[O:28])[O:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 15891Phenyl chloroformateHCID 81531DiisopropylethylamineHCID 71208533Methyl 3-(aminomethyl)-7-chloro-4-oxo-1-phenylquinoline-2-carboxylate

Product 1

HCID 718111377-Chloro-4-oxo-3-(phenoxycarbonylamino-methyl)-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester

Sources & evidence

ORD record
ord-68f356a2a040418f87ca91b3996fbbca
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…