Hydroxylamine → HCID 178513281, compound

HRID 900174Notes

Reaction equation

HRID 900174 reaction equation
[C:1](#[N:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:9][OH:10]>C(O)C>[OH:10][NH:9][C:1](=[NH:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 787HydroxylamineHCID 7505Benzonitrile

Product 1

HCID 178513281HCID 178513281, compoundYield 68.9%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Benzonitrile (5 g, 48 mmol) was dissolved in ethanol (100 ml) and treated with 50% aqueous hydroxylamine (16 ml, 242 mmol). Reaction was heated to reflux for 3 hours before concentration under reduced pressure to give a clear foam (4.5 g, 68%).

Workup

  1. customReaction
  2. temperaturewas heated
  3. temperatureto reflux for 3 hours before concentration under reduced pressure

Sources & evidence

ORD record
ord-75c46b488b9e4b259aa262037b85e2e5
Source dataset
uspto-grants-2008_04
Patent number
US07358265B2

Reaction notes

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