反应详情

To a dichloromethane solution of 5-pyridin-3-yl-2H-[1,2,4]triazole-3-thiol (Step B, Example 1) triethylamine was added followed by iodomethane. This solution was stirred at room temperature for 2 h, during which period the reaction was complete by RP-HPLC. The solvent was evaporated and the residue was purified by RP-HPLC affording the desired intermediate.

1. customThe solvent was evaporated
2. customthe residue was purified by RP-HPLC