反应详情

Urocanic acid (compound i, where R2 is H)(1.38 g, 10.0 mmol) was dissolved in 5% aqueous HCl (20 ml) plus MeOH (15 ml) containing 10% Pd on carbon (100 mg) and the mixture was shaken overnight under about 30 psi H2. The catalyst was removed by filtration through a 3 cm pad of diatomaceous earth and the filtrate was concentrated to a solid and dried overnight under vacuum. The crude material was used without further purification. Mass spec. 141.4 MH+

1. customThe catalyst was removed by filtration through a 3 cm pad of diatomaceous earth
2. concentrationthe filtrate was concentrated to a solid
3. customdried overnight under vacuum
4. customThe crude material was used without further purification