反应详情

A suspension of 3B (350 mg, 1.458 mmol) and palladium (5% wt) on activated carbon (300 mg) in EtOAc(100 mL) and MeOH (200 mL) was stirred under a hydrogen balloon for 1 hour. The reaction mixture was filtered via a pad of Celite. The filtrate was concentrated under reduced pressure to give the title compound as a light brown solid (305 mg, 99% yield). LC/MS (method A): retention time=1.60 min, (M+H)+=211.

1. filtrationThe reaction mixture was filtered via a pad of Celite
2. concentrationThe filtrate was concentrated under reduced pressure