反应详情

温度

90 °C

2.06 g (20.0 mmol) of 5-amino-1-pentanol was dissolved in 5 mL of ethyl formate and the mixture was stirred at 90° C. for 4 hours. The solvent was distilled off under reduced pressure and the obtained residue was purified by silica gel chromatography (eluting solvent: ethyl acetate/methanol=100/0-70/30) to obtain 1.90 g (yield: 73%) of the title compound as a pale yellow-oil.

1. distillationThe solvent was distilled off under reduced pressure
2. customthe obtained residue was purified by silica gel chromatography (eluting solvent: ethyl acetate/methanol=100/0-70/30)