反应详情

Treatment of 2′-chloro-2-fluoro-6-methoxybiphenyl (17.0 g) with hydrogen bromide (33% in acetic acid, 60 mL) according to the procedure described for Example 69, Step 2 provided 7.5 g (57%) of 2′-chloro-6-fluorobiphenyl-2-ol as a colorless oil.