反应详情

Treatment of 2′,4′-dichloro-6-fluorobiphenyl-2-ol (1.6 g, 6.2 mmol) with potassium carbonate (1.3 g, 9.3 mmol) and allyl bromide (0.79 mL, 9.3 mmol) in DMSO (50 mL) according to the procedure described for Example 69, Step 3 provided 1.7 g (92%) of 2′-allyloxy-2,4-dichloro-6′-fluorobiphenyl as a pale yellow oil.