Methylamine → HCID 178485194, compound

HRID 903098Notes

Reaction equation

HRID 903098 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([C:12]([N+:16]([O-])=O)=[N:13][O:14][CH3:15])[CH2:9][N:8]=[C:7]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=3[F:25])[C:6]=2[CH:26]=1.[CH3:27]N>C(O)C>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([C:12](=[N:13][O:14][CH3:15])[NH:16][CH3:27])[CH2:9][N:8]=[C:7]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=3[F:25])[C:6]=2[CH:26]=1

Participants

4

Reactant 2

HCID 6329MethylamineHCID 54384993HCID 54384993, compound

Product 1

HCID 178485194HCID 178485194, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Reaction of 0.5 g of 7-chloro-5-(2-fluorophenyl)-N-methoxy-α-nitro-3H-1,4-benzodiazepine-2-methanimine with methylamine in ethanol (20% v/v) gave the same workup and purification procedure colorless product, crystallized from ether/hexane; mp 140°-142° C.

Workup

  1. customgave
  2. customthe same workup and purification procedure colorless product
  3. customcrystallized from ether/hexane

Sources & evidence

ORD record
ord-49293084aa2146df9df01bf4351e6b09
Source dataset
uspto-grants-1980_10
Patent number
US04226768

Reaction notes

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