Ethyl formate → HCID 20279269, compound

HRID 903355Notes

Reaction equation

HRID 903355 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9].[CH:13](OCC)=[O:14].[H-].[Na+]>COCCOC>[CH:13]([CH:7]([CH2:6][C:2]1[O:1][CH:5]=[CH:4][CH:3]=1)[C:8]([O:10][CH2:11][CH3:12])=[O:9])=[O:14]

Participants

5

Reactant 3

HCID 8025Ethyl formateHCID 24758Sodium hydrideHCID 61450Ethyl 2-furanpropionate

Product 1

HCID 20279269HCID 20279269, compoundYield 75%

Reagents, catalysts & solvents 1

HCID 80711,2-DimethoxyethaneSolvent

Procedure

Ethyl 3-(2-furyl)propionate was reacted with 1.1 equivalents ethyl formate and 1.0 equivalents sodium hydride in 1,2-dimethoxyethane at room temperature to give ethyl 2-formyl-3-(2-furyl)propionate as an oil in 75% yield.

Sources & evidence

ORD record
ord-43b611aab8f04470814ebbce57c74360
Source dataset
uspto-grants-1980_10
Patent number
US04227000

Reaction notes

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