Carbon Dioxide → HCID 23335081, compound

HRID 903812Notes

Reaction equation

HRID 903812 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[NH:9][S:10]([C:13]1[CH:24]=[C:17]2[C:18](OC(=O)[NH:22][C:16]2=[CH:15][CH:14]=1)=O)(=[O:12])=[O:11].C(=O)=O.O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O.[C:42]([NH:50][NH2:51])(=[O:49])[C:43]1[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=1>CN1CCCC1=O>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[NH:9][S:10]([C:13]1[CH:14]=[CH:15][C:16]([NH2:22])=[C:17]([C:18]2[O:49][C:42]([C:43]3[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=3)=[N:50][N:51]=2)[CH:24]=1)(=[O:11])=[O:12]

Participants

6

Reactant 4

HCID 280Carbon DioxideHCID 11955BenzoylhydrazineHCID 14812Phosphorus oxide (P4O10)HCID 54244768HCID 54244768, compound

Product 1

HCID 23335081HCID 23335081, compound

Reagents, catalysts & solvents 1

HCID 13387N-methyl-2-pyrrolidoneSolvent

Conditions

Temperature
120 °C

Procedure

97 Parts of this isatoic anhydride are dissolved in 200 parts of N-methylpyrrolidone and 35 parts of benzhydrazide are added. The mixture is stirred at 120° C. until the evolution of CO2 is ceased, 35 parts of phosphorus pentoxide are then added and the batch is stirred for a further 4 hours at 120° C. After cooling, the product is precipitated with water, filtered off, rinsed with water and dried. This gives 107 parts of 4-[2,4-dichlorophenyl-sulfamoyl]-2 [5-phenyl-1,3,4-oxdiazolyl]-aniline of meltingpoint 215°-220° C.

Workup

  1. additionare added
  2. temperatureAfter cooling
  3. customthe product is precipitated with water
  4. filtrationfiltered off
  5. washrinsed with water
  6. customdried

Sources & evidence

ORD record
ord-c4eab1791cab4a7c955faf08cf19603f
Source dataset
uspto-grants-1980_10
Patent number
US04229343

Reaction notes

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