Methylamine → HCID 13464010, compound

HRID 903891Notes

Reaction equation

HRID 903891 reaction equation
[CH3:1][NH2:2].[CH3:3][C:4]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[C:12](=O)[C:7]2[CH:8]=[N:9][CH:10]=[CH:11][C:6]=2[CH:5]=1.C(=O)([O-])[O-].[K+].[K+]>C1C=CC=CC=1.[Ti](Cl)(Cl)(Cl)Cl>[CH3:3][C:4]1[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=2[C:12](=[N:2][CH3:1])[C:7]2[CH:8]=[N:9][CH:10]=[CH:11][C:6]=2[CH:5]=1

Participants

6

Reactant 3

HCID 6329MethylamineHCID 11430Potassium CarbonateHCID 13464009HCID 13464009, compound

Product 1

HCID 13464010HCID 13464010, compound

Reagents, catalysts & solvents 2

HCID 24193Titanium TetrachlorideCatalystHCID 241BenzeneSolvent2×

Procedure

A solution of titanium tetrachloride (0.7 ml., 0.006 mole) in benzene (20 ml.) is added rapidly to a stirred solution of methylamine (1.24 g., 0.04 mole) and 6-methylbenzo[5,6]cyclohepta[1,2-c]pyridin-11-one (2.21 g., 0.01 mole) in benzene (150 ml.). After 4 hours, anhydrous potassium carbonate is added and the reaction mixture is filtered. The filtrate is evaporated to a pale yellow oil, (2.95 g.).

Workup

  1. filtrationthe reaction mixture is filtered
  2. customThe filtrate is evaporated to a pale yellow oil, (2.95 g.)

Sources & evidence

ORD record
ord-8645f84dd0ff4f0389c5db69363e9775
Source dataset
uspto-grants-1980_10
Patent number
US04229455

Reaction notes

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