Chlorosuccinimide → HCID 23333584, compound

HRID 904196Notes

Reaction equation

HRID 904196 reaction equation
[CH3:1][N:2]1[CH2:8][C:7]2[CH:9]=[CH:10][CH:11]=[CH:12][C:6]=2[C:5](=[O:13])[C:4]2[CH:14]=[C:15]([CH:18]([CH3:23])[C:19]([O:21]C)=[O:20])[CH:16]=[CH:17][C:3]1=2.[Cl:24]N1C(=O)CCC1=O>C(Cl)(Cl)Cl>[Cl:24][C:17]1[C:3]2[N:2]([CH3:1])[CH2:8][C:7]3[CH:9]=[CH:10][CH:11]=[CH:12][C:6]=3[C:5](=[O:13])[C:4]=2[CH:14]=[C:15]([CH:18]([CH3:23])[C:19]([OH:21])=[O:20])[CH:16]=1

Participants

4

Reactant 2

HCID 31398ChlorosuccinimideHCID 23333581HCID 23333581, compound

Product 1

HCID 23333584HCID 23333584, compoundYield 79.7%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Methyl 2-(5,6-dihydro-5-methyl-11-oxodibenz[b,e]azepin-2-yl)propionate (2.0 g), chloroform (50 ml) and N-chlorosuccinimide (1.4 g) were treated in the same manner as described in Example 9 to obtain the desired compound (1.7 g) as a yellow oily material.

Sources & evidence

ORD record
ord-75aaecb5ad0f4390a245b72a65e70d11
Source dataset
uspto-grants-1980_10
Patent number
US04230703

Reaction notes

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