Hydrochloric Acid → 4-(15-Carboxypentadecylamino)benzonitrile

HRID 904246Notes

Reaction equation

HRID 904246 reaction equation
[C:1]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][NH:20][C:21]1[CH:28]=[CH:27][C:24]([C:25]#[N:26])=[CH:23][CH:22]=1)([O:3]C)=[O:2].[OH-].[K+].C(O)C.Cl>O>[C:1]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][NH:20][C:21]1[CH:28]=[CH:27][C:24]([C:25]#[N:26])=[CH:23][CH:22]=1)([OH:3])=[O:2]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 14797Potassium HydroxideHCID 211633764-(15-Carbomethoxypentadecylamino)benzonitrile

Product 1

HCID 211633634-(15-Carboxypentadecylamino)benzonitrile

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 3 g. of 4-(15-carbomethoxypentadecylamino)benzonitrile and 0.5 g. of potassium hydroxide in 50 ml. of 95% ethanol is stirred at 50° C. for 10 hours, diluted with water and acidified with dilute hydrochloric acid. The precipitate is collected, dried and recrystallized from ether-hexane to yield 4-(15-carboxypentadecylamino)benzonitrile as a white solid.

Workup

  1. customThe precipitate is collected
  2. customdried
  3. customrecrystallized from ether-hexane

Sources & evidence

ORD record
ord-1fef47bf7d7c45e9b32c210980f0d9a9
Source dataset
uspto-grants-1980_10
Patent number
US04230628

Reaction notes

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