Glycerol → HCID 54219665, compound

HRID 904491Notes

Reaction equation

HRID 904491 reaction equation
[CH2:1]([NH:15][C:16]1[CH:25]=[CH:24][C:19]([C:20]([O:22][CH3:23])=[O:21])=[CH:18][CH:17]=1)[CH2:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].C1(C)C=CC(S(O)(=O)=O)=CC=1.[OH:37][CH2:38][CH:39](CO)[OH:40]>>[CH2:1]([NH:15][C:16]1[CH:17]=[CH:18][C:19]([C:20]([O:22][CH2:23][CH:39]([OH:40])[CH2:38][OH:37])=[O:21])=[CH:24][CH:25]=1)[CH2:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

Participants

4

Reactant 3

HCID 753GlycerolHCID 6101p-Toluenesulfonic acidHCID 54481030HCID 54481030, compound

Product 1

HCID 54219665HCID 54219665, compound

Procedure

A mixture of 2.25 g. of methyl 4-(4-tetradecenylamino)benzoate, 280 mg. of glycerol, and 1.37 g. of p-toluenesulfonic acid is heated at 180° C. for 18 hours and then is partitioned between ether and 3% aqueous sodium carbonate solution. The ether layer is separated, dried, and evaporated to yield the product as a white solid.

Workup

  1. additionA mixture of 2.25 g
  2. customis partitioned between ether and 3% aqueous sodium carbonate solution
  3. customThe ether layer is separated
  4. customdried
  5. customevaporated

Sources & evidence

ORD record
ord-f019ec76298a4516a3a58f0dbf2d1c80
Source dataset
uspto-grants-1980_10
Patent number
US04230878

Reaction notes

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