HCID 150640, compound → 6-chloro-4-oxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylate

HRID 904665Notes

Reaction equation

HRID 904665 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[C:7]([CH2:20][CH2:21][CH3:22])[C:8]3[O:15][C:14]([C:16]([OH:18])=[O:17])=[CH:13][C:12](=[O:19])[C:9]=3[CH:10]=2)[N:5]=[C:4]([C:23]([OH:25])=[O:24])[CH:3]=1.C(=O)(O)[O-].[Na+:30]>O>[Cl:1][C:2]1[C:11]2[C:6](=[C:7]([CH2:20][CH2:21][CH3:22])[C:8]3[O:15][C:14]([C:16]([O-:18])=[O:17])=[CH:13][C:12](=[O:19])[C:9]=3[CH:10]=2)[N:5]=[C:4]([C:23]([O-:25])=[O:24])[CH:3]=1.[Na+:30].[Na+:30]

Participants

4

Reactant 2

HCID 150640HCID 150640, compoundHCID 516892Sodium Bicarbonate

Product 1

HCID 30365866-chloro-4-oxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylateYield 85.1%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

6-Chloro-4-oxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid (0.629 g) suspended in water was treated with sodium bicarbonate (0.292 g) and stirred until complete dissolution occurred. The solution was filtered then treated with acetone. The precipitated product was collected by filtration and dried to give (0.6 g) of the title compound.

Workup

  1. filtrationThe solution was filtered
  2. additionthen treated with acetone
  3. filtrationThe precipitated product was collected by filtration
  4. customdried

Sources & evidence

ORD record
ord-80634630f281496f824dae5bc16c3208
Source dataset
uspto-grants-1983_12
Patent number
US04419352

Reaction notes

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