Ammonium → 3-Phenylpyrrolidine-2,5-dione

HRID 904719Notes

Reaction equation

HRID 904719 reaction equation
[C:1]1([CH:7]2[CH2:12][C:11](=[O:13])O[C:8]2=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.[NH4+:15]>>[C:1]1([CH:7]2[C:8](=[O:9])[NH:15][C:11](=[O:13])[CH2:12]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 223AmmoniumHCID 313Hydrochloric AcidHCID 136911Phenylsuccinic Anhydride

Product 1

HCID 5688903-Phenylpyrrolidine-2,5-dione

Procedure

10 g of phenylsuccinic anhydride was gradually added to 20 ml of 28% aqueous ammonium solution and the mixture was stirred for about 1 hour. To the reaction mixture was added aqueous hydrochloric acid solution so as to neutralize. After cooling, crystals thus formed were collected by filtration to obtain about 8.2 g of 3-phenylsuccinimide.

Workup

  1. temperatureAfter cooling
  2. customcrystals thus formed
  3. filtrationwere collected by filtration

Sources & evidence

ORD record
ord-bf1f87100fec4ba190b33c453698846e
Source dataset
uspto-grants-1983_12
Patent number
US04419443

Reaction notes

Loading…