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HRID904829

反应详情

EQUATION

反应方程式

HRID 904829 的结构方程式

REACTANTS

反应物

3
结构：CC(=O)N(C)[Si](C)(C)C
HCID81953

Acetamide, N-methyl-N-(trimethylsilyl)-

C6H15NOSi

结构：CC(C)S(=O)(=O)n1c(N)nc2ccc(C(=O)c3ccccc3)cc21
HCID3017389

[2-Imino-3-(propane-2-sulfonyl)-2,3-dihydro-1H-benzimidazol-5-yl](phenyl)methanone

C17H17N3O3S

结构：[Li]CCCC
HCID178418339

Butyllithium

C4H9Li

PRODUCTS

生成物

1
结构：CNC(=O)CC(O)(c1ccccc1)c1ccc2nc(N)n(S(=O)(=O)C(C)C)c2c1
HCID13286499

未命名化合物

PROCEDURE

实验过程

Following the general procedure of Example 23, N-methyl-N-trimethylsilylacetamide was reacted with 1-isopropylsulfonyl-2-amino-6-benzoylbenzimidazole in the presence of n-butyl lithium to provide 1-isopropylsulfonyl-2-amino-6-(α-hydroxy-α-methylaminocarbonylmethylbenzyl)benzimidazole. M.P. 92°-95° C.