反应详情

18.6 g (50 mmoles) of Z-Tyr(But)-OH in 30 ml of pyridine are reacted with 30 ml of isopropanol and 40 ml of a 50 percent solution of propylphosphonic anhydride in methylene chloride analogously to Example 30 A. The resulting oil is subjected to catalytic hydrogenation analogously to Example 25 B. The substance crystallizes from ether. Yield 13.15 g (83%), melting point 161°-163°, [α]D23 =+15.7° (c=1, methanol).

1. customThe substance crystallizes from ether
2. customYield 13.15 g (83%), melting point 161°-163°, [α]D23 =+15.7° (c=1, methanol)