反应详情

A solution of 121 mg of trans-6-(4-chlorobenzyloxymethyl)-2-[2-bromo-1-(2,4-dichlorophenyl)ethoxy]tetrahydropyran, 73 mg of imidazole and 81 mg of sodium iodide in 3 ml of dimethylformamide was heated, with stirring, at 130°-140° C. for 6 hours, after which the mixture was treated and the product purified essentially as described in Example 34(b)(i), to give 66 mg of the title compound, in the form of a colourless oil.

1. additionafter which the mixture was treated
2. customthe product purified essentially