Ethanol → HCID 3067727, compound

HRID 905106Notes

Reaction equation

HRID 905106 reaction equation
[ClH:1].[NH2:2][OH:3].[N:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH2:10]([OH:12])[CH3:11]>>[Cl:1][C:6]1[CH:5]=[C:8]2[C:9](=[CH:8][CH:7]=1)[N:4]([C:10](=[O:12])[CH3:11])[CH2:5][CH2:6][C:7]2=[N:2][OH:3]

Participants

4

Reactant 3

HCID 702EthanolHCID 1049PyridineHCID 443297Hydroxyamine hydrochloride

Product 1

HCID 3067727HCID 3067727, compound

Procedure

Then, the above product was dissolved in 300 ml of ethanol, to which were added 15.64 parts of hydroxylamine hydrochloride and 17.8 parts of pyridine, and the reaction was effected under reflux for 1.5 hours. Thereafter, the product was treated as in Example 1 to obtain 20.4 parts of 6-chloro-4-oximino-1-acetyl-1,2,3,4-tetrahydroquinoline as white crystals.

Workup

  1. temperatureunder reflux for 1.5 hours
  2. additionThereafter, the product was treated as in Example 1

Sources & evidence

ORD record
ord-8d4220ad08504bc1ad08152e1cef24dd
Source dataset
uspto-grants-1983_12
Patent number
US04421919

Reaction notes

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