Hydrazine hydrate (1:1) → HCID 13014243, compound

HRID 905141Notes

Reaction equation

HRID 905141 reaction equation
C([O:3][C:4](=O)[CH2:5][NH:6][C:7]1[C:12]([CH2:13][CH3:14])=[CH:11][CH:10]=[CH:9][C:8]=1[CH2:15][CH3:16])C.O.[NH2:19][NH2:20]>C(O)C>[CH2:15]([C:8]1[CH:9]=[CH:10][CH:11]=[C:12]([CH2:13][CH3:14])[C:7]=1[NH:6][CH2:5][C:4]([NH:19][NH2:20])=[O:3])[CH3:16]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 170107Glycine, N-(2,6-diethylphenyl)-, ethyl ester

Product 1

HCID 13014243HCID 13014243, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

58.7 g (0.25 mol) of 2,6-diethyl-anilino-acetic acid ethyl ester and 25 g of hydrazine hydrate were left to stand in 200 ml of ethanol for 24 hours. Thereafter, the mixture was concentrated by distilling off the solvent and the residue was extracted by stirring with water. After drying, 50.5 g (91% of theory) of colorless crystals of 2,6-diethyl-anilino-acetic acid hydrazide of melting point 71° to 73° C. were obtained.

Workup

  1. concentrationThereafter, the mixture was concentrated
  2. distillationby distilling off the solvent
  3. extractionthe residue was extracted
  4. customAfter drying

Sources & evidence

ORD record
ord-c9da13cbc97e45b280ec8b19510975b9
Source dataset
uspto-grants-1983_12
Patent number
US04422866

Reaction notes

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