Heptane → 5-Bromo-2-(methanesulfinyl)pyrimidine

HRID 905236Notes

Reaction equation

HRID 905236 reaction equation
[CH3:1][S:2][C:3]1[N:8]=[CH:7][C:6]([Br:9])=[CH:5][N:4]=1.ClC1C=CC=C(C(OO)=[O:18])C=1.CCCCCCC>C(Cl)(Cl)Cl>[CH3:1][S:2]([C:3]1[N:8]=[CH:7][C:6]([Br:9])=[CH:5][N:4]=1)=[O:18]

Participants

5

Reactant 3

HCID 8900HeptaneHCID 70297m-Chloroperbenzoic acidHCID 47385645-Bromo-2-(methylsulfanyl)pyrimidine

Product 1

HCID 204757015-Bromo-2-(methanesulfinyl)pyrimidineYield 90%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

The title compound was prepared by oxidation of 2-methylthio-5-bromopyrimidine by m-chloroperbenzoic acid in chloroform as described in Example 39; yield 90%, m.p. 90° C. (n-heptane). 1H NMR (CDCl3): δ2.91 (Me),. 8.90 (H-4, H-6).

Sources & evidence

ORD record
ord-10c85693b78c43fdb9cd41e7d79a859e
Source dataset
uspto-grants-1983_12
Patent number
US04423047

Reaction notes

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