Acetonitrile → 4-[3-tert-Butoxycarbonylaminopyrrolidin-1-yl]-3-chloro-2,5-difluorobenzoic acid ethyl ester
Reaction equation
[C:23]([CH3:24])([CH3:25])([CH3:26])[O:27][C:28]([NH:29][CH:30]1[CH2:31][NH:32][CH2:33][CH2:34]1)=[O:35].[CH2:1]([CH3:2])[O:3][C:4]([c:5]1[c:6]([F:14])[c:7]([Cl:13])[c:8]([F:12])[c:9]([F:11])[cH:10]1)=[O:15].[CH3:16][CH2:17][N:18]([CH2:19][CH3:20])[CH2:21][CH3:22].[CH3:36][C:37]#[N:38].[CH3:39][CH2:40][O:41][C:42](=[O:43])[CH3:44]>>[CH2:1]([CH3:2])[O:3][C:4]([c:5]1[c:6]([F:14])[c:7]([Cl:13])[c:8]([N:32]2[CH2:31][CH:30]([NH:29][C:28]([O:27][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:35])[CH2:34][CH2:33]2)[c:9]([F:11])[cH:10]1)=[O:15]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6d51cc7310f94ac2801d0409eb9057f6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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