反应详情

To a solution of the compound (506 mg) obtained in Example 1 in chloroform (5 ml) was added, with stirring at room temperature, triethylamine (167 μl), and 9-fluorenylmethoxycarbonyl isothiocyanate (281 mg) was added. After stirring overnight at room temperature, piperidine (198 μl) was added. After stirring overnight at room temperature, the reaction mixture was concentrated under reduced pressure, and purified by column chromatography (3% methanol/chloroform) to give the title compound (442 mg).

1. stirringAfter stirring overnight at room temperature
2. stirringAfter stirring overnight at room temperature
3. concentrationthe reaction mixture was concentrated under reduced pressure
4. custompurified by column chromatography (3% methanol/chloroform)