反应详情

A solution of the compound (4.25 g) obtained in Step 5 in N,N-dimethylformamide (128 ml) was stirred at 130° C. for 14 hr. The reaction mixture was concentrated under reduced pressure, xylene was added to the residue, and the mixture was concentrated again under reduced pressure. The obtained crude crystals were suspended in ethyl acetate, collected by filtration and dried to give the title compound (3.35 g).

1. concentrationThe reaction mixture was concentrated under reduced pressure, xylene
2. additionwas added to the residue
3. concentrationthe mixture was concentrated again under reduced pressure
4. customThe obtained crude crystals
5. filtrationcollected by filtration
6. customdried