反应详情

The compound (788 mg) obtained in Step 3 was suspended in ethanol (7.8 ml), and hydrazine monohydrate (243 μl) and acetic acid (780 μl) were added, with stirring at room temperature. The mixture was stirred overnight at a bath temperature of 100° C. and returned to room temperature. The reaction mixture was concentrated under reduced pressure, and the obtained crude crystals were suspended in methanol, collected by filtration and dried to give the title compound (690 mg).

1. stirringThe mixture was stirred overnight at a bath temperature of 100° C.
2. customreturned to room temperature
3. concentrationThe reaction mixture was concentrated under reduced pressure
4. customthe obtained crude crystals
5. filtrationcollected by filtration
6. customdried