Triethylamine → HCID 15758917, compound

HRID 908897Notes

Reaction equation

HRID 908897 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][OH:11])=[CH:4][CH:3]=1.C(N(CC)CC)C.[CH3:19][S:20](Cl)(=[O:22])=[O:21]>ClCCl>[S:20]([O:11][CH2:10][CH2:9][CH2:8][C:5]1[CH:6]=[CH:7][C:2]([CH3:1])=[CH:3][CH:4]=1)(=[O:22])(=[O:21])[CH3:19]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 2218933-(4-Methylphenyl)propan-1-ol

Product 1

HCID 15758917HCID 15758917, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Following the procedure described in example 1§B, but starting from 3-(4-methylphenyl)propan-1-ol (6.02 g), triethylamine (2.9 mL), methanesulfonyl chloride (3.67 mL) and dichloromethane (39 mL), affords 3-(4-methylphenyl)propan-1-ol mesylate (3.4 g) used without further purification.

Sources & evidence

ORD record
ord-d74b549362eb489c93859f0f913ceed9
Source dataset
uspto-grants-2011_09
Patent number
US08017646B2

Reaction notes

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