Methane → Ethyl 2-(4-aminophenyl)-1-cyclopentylbenzimidazole-5-carboxylate

HRID 90954Notes

Reaction equation

HRID 90954 reaction equation
[C:37].[CH2:34]([OH:35])[CH3:36].[CH:1]1([n:6]2[c:7](-[c:20]3[cH:21][cH:22][c:23]([N+:26]([O-:27])=[O:28])[cH:24][cH:25]3)[n:8][c:9]3[c:10]2[cH:11][cH:12][c:13]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[cH:14]3)[CH2:2][CH2:3][CH2:4][CH2:5]1.[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1.[Pd:38]>>[CH:1]1([n:6]2[c:7](-[c:20]3[cH:21][cH:22][c:23]([NH2:26])[cH:24][cH:25]3)[n:8][c:9]3[c:10]2[cH:11][cH:12][c:13]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[cH:14]3)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

6

Reactant 5

HCID 297MethaneHCID 702EthanolHCID 8028TetrahydrofuranHCID 23938PalladiumHCID 10293086Ethyl 1-cyclopentyl-2-(4-nitrophenyl)benzimidazole-5-carboxylate

Product 1

HCID 10132552Ethyl 2-(4-aminophenyl)-1-cyclopentylbenzimidazole-5-carboxylate

Sources & evidence

ORD record
ord-e8063eb0e31a42ae884d3ab417da16f6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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