反应详情

A mixture of the product from step (i) (1.60 g), potassium carbonate (0.934 g) and 2-fluoro-4-chloro-nitrobenzene (1.18 g) in DMF (20 ml) was stirred at RT overnight. Water (200 ml) was added and the mixture extracted with ethyl acetate. The organics were dried, evaporated under reduced and the residue purified by chromatography on silica eluting with isohexane/diethylether 4:1, yield 0.80 g.

1. extractionthe mixture extracted with ethyl acetate
2. customThe organics were dried
3. customevaporated
4. customthe residue purified by chromatography on silica eluting with isohexane/diethylether 4:1, yield 0.80 g