Hydrochloric Acid → N-[2-(t-butyldimethylsilanyloxy)-ethoxy]-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-5-(hydroxyiminomethyl)-benzamide
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][CH2:8][O:9][NH:10][C:11]([c:12]1[c:13]([NH:22][c:23]2[c:24]([F:30])[cH:25][c:26]([I:29])[cH:27][cH:28]2)[c:14]([F:21])[c:15]([F:20])[c:16]([CH:18]=[O:19])[cH:17]1)=[O:31])([CH3:32])[CH3:33].[C:37](=[O:38])([OH:39])[O-:40].[CH3:43][CH2:44][OH:45].[ClH:34].[NH2:35][OH:36].[Na+:41].[OH2:42]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][CH2:8][O:9][NH:10][C:11]([c:12]1[c:13]([NH:22][c:23]2[c:24]([F:30])[cH:25][c:26]([I:29])[cH:27][cH:28]2)[c:14]([F:21])[c:15]([F:20])[c:16]([CH:18]=[N:35][OH:36])[cH:17]1)=[O:31])([CH3:32])[CH3:33]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-2a601770e75e46b19b876a954a1adf37
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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