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HRID9142

反应详情

EQUATION

反应方程式

HRID 9142 的结构方程式

REACTANTS

反应物

4
结构：CC(=O)O
HCID176

Acetic Acid

C2H4O2

结构：CCN(CC)CC
HCID8471

Triethylamine

C6H15N

结构：CN(C)c1ccc(C(=O)Cl)cc1
HCID4400782

4-(Dimethylamino)benzoyl chloride

C9H10ClNO

结构：CCNC(=O)Nc1nc2ccc(C(=O)CCN)cc2s1
HCID21985556

未命名化合物

PRODUCTS

生成物

1
结构：CCNC(=O)Nc1nc2ccc(C(=O)CCNC(=O)c3ccc(N(C)C)cc3)cc2s1
HCID21985527

未命名化合物

收率 25%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

Similar to the synthesis of Example 248, a mixture of 1-(6-(3-aminopropanoyl)-2-benzothiazolyl)-3-ethylurea, triethylamine and 4-dimethylaminobenzoyl chloride in DMF was reacted to give the desired compound 0.025 g (25%) as an acetic acid salt. LC/MS 440.1 (M+1); LC retention time 2.86 min.

WORKUP

后处理

  1. customSimilar to the synthesis of Example 248
  2. customwas reacted