Tetrahydrofuran → 2-[1-[1-Benzyl-4-(4-chloro-3-fluorophenyl)pyrrolidin-3-yl]ethoxy]-5-chloropyridine
Reaction equation
[CH2:28]([c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1)[N:35]1[CH2:36][CH:37]([CH:48]([CH3:49])[OH:50])[CH:38]([c:40]2[cH:41][c:42]([F:47])[c:43]([Cl:46])[cH:44][cH:45]2)[CH2:39]1.[CH2:51]1[O:52][CH2:53][CH2:54][CH2:55]1.[Cl:20][c:21]1[cH:22][cH:23][c:24]([OH:27])[n:25][cH:26]1.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[Cl:20][c:21]1[cH:22][cH:23][c:24]([O:27][CH:48]([CH:37]2[CH2:36][N:35]([CH2:28][c:29]3[cH:30][cH:31][cH:32][cH:33][cH:34]3)[CH2:39][CH:38]2[c:40]2[cH:41][c:42]([F:47])[c:43]([Cl:46])[cH:44][cH:45]2)[CH3:49])[n:25][cH:26]1Participants
5
Sources & evidence
- ORD record
- ord-272672874c264f28afd83886f636cfd6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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