Diisopropylamine → Methyl 4-(pyrrolidin-1-ylcarbonyl)-3-(2-trimethylsilylethynyl)benzoate
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][CH3:8])[cH:9][cH:10][c:11]1[C:12](=[O:13])[N:14]1[CH2:15][CH2:16][CH2:17][CH2:18]1.[CH3:19][Si:20]([CH3:21])([CH3:22])[C:23]#[CH:24].[CH3:32][CH2:33][O:34][C:35](=[O:36])[CH3:37].[CH:25]([NH:26][CH:27]([CH3:28])[CH3:29])([CH3:30])[CH3:31]>>[c:2]1([C:24]#[C:23][Si:20]([CH3:19])([CH3:21])[CH3:22])[cH:3][c:4]([C:5](=[O:6])[O:7][CH3:8])[cH:9][cH:10][c:11]1[C:12](=[O:13])[N:14]1[CH2:15][CH2:16][CH2:17][CH2:18]1Participants
5
Sources & evidence
- ORD record
- ord-fc7d7162019942e6b65970d768345c4f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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