反应详情

温度

70 °C

A mixture of 163 (1.72 g, 4.6 mmol) and hydrazine monohydrate (0.95 g, 19 mmol) in EtOH (20 mL) is heated at 70° C. overnight. The solvent is removed in vacuo and the residue is triturated with ethyl acetate and ethyl ether. Filtration gives the product (164) as a white solid.

1. customThe solvent is removed in vacuo
2. customthe residue is triturated with ethyl acetate and ethyl ether
3. filtrationFiltration