反应详情

温度

75 °C

To a solution of the ketone product from Step A (5.48 g, 20.67 mmol) in DMF (70 mL) was added N,N-dimethylformamide dimethyl acetal (9.89 g, 82.7 mmol). The reaction was stirred at 75° C. for 16 hours. Most of the volatiles were removed in vacuo to afford the crude product as an oil which was used in the next step (Step C) without further purification.

1. customMost of the volatiles were removed in vacuo